What is ARPKD?
Autosomal Recessive Polycystic Kidney Disease (ARPKD) is a rare genetic disorder that causes cysts to develop in the kidneys and liver. The condition primarily affects infants and children.
Key Features
- Inherited genetic condition
- Affects approximately 1 in 20,000 children
- Causes fluid-filled cysts in kidneys and liver
- Can be diagnosed before birth or in early childhood
Symptoms and Signs
Kidney Symptoms
- Enlarged kidneys
- High blood pressure
- Urinary tract infections
- Decreased urination
- Poor kidney function
Liver Symptoms
- Enlarged liver
- Portal hypertension
- Bile duct problems
Diagnosis
- Prenatal ultrasound
- Genetic testing
- Family history evaluation
- Imaging studies (MRI, CT)
Treatment Options
Managing Kidney Disease
- Blood pressure medications
- Dialysis when needed
- Kidney transplantation
- Regular monitoring
Managing Liver Complications
- Medication for portal hypertension
- Liver transplantation if necessary
Living with ARPKD
Daily Management
- Regular medical check-ups
- Dietary modifications
- Medication compliance
- Monitoring blood pressure
Long-term Outlook
- Varies among individuals
- Early diagnosis improves outcomes
- Regular medical care essential
Support and Resources
- Genetic counseling
- Support groups
- PKD Foundation
- Medical specialist team
When to Seek Medical Attention
- Unexplained fever
- Severe abdominal pain
- Changes in urination
- Worsening blood pressure