Comprehensive Tumor Biopsy Protocol

Pre-Procedure Requirements

Patient Preparation

• Complete coagulation profile (PT, PTT, INR)
• CBC with platelets
• Recent imaging studies review
• Informed consent documentation
• NPO status as required

Equipment Preparation

• Core needle biopsy set (14-18 gauge)
• Fine needle aspiration supplies (22-25 gauge)
• Sterile field setup
• Local anesthetic (1-2% lidocaine)
• Specimen containers with fixative
• Imaging guidance equipment as needed

Procedure Steps

1. Initial Assessment

• Verify patient identity and biopsy site
• Review relevant imaging
• Mark optimal biopsy approach
• Position patient appropriately

2. Sterile Technique

• Perform surgical hand scrub
• Don sterile PPE
• Prepare site with chlorhexidine/betadine
• Apply sterile drapes

3. Biopsy Execution

1. Administer local anesthetic
2. Make small incision if needed
3. Insert biopsy needle under guidance
4. Obtain adequate tissue samples (minimum 3-5 cores)
5. Apply pressure for hemostasis

4. Specimen Handling

• Label specimens immediately
• Document number and size of cores
• Place in appropriate fixative
• Submit rush specimens to pathology

Post-Procedure Protocol

Immediate Care

• Monitor vital signs q15min x1hr
• Assess biopsy site
• Provide post-procedure instructions

Documentation Requirements

• Procedure note
• Specimen documentation
• Post-procedure orders
• Follow-up scheduling

Quality Metrics

Success Indicators

• Adequate tissue yield
• Proper specimen preservation
• Minimal complications
• Diagnostic accuracy

Risk Management

• Document complications
• Track specimen adequacy rates
• Monitor diagnostic yield