What is Corticobasal Degeneration?
Corticobasal degeneration (CBD) is a rare, progressive neurological disorder that affects movement and cognitive function. It primarily impacts the cerebral cortex and basal ganglia regions of the brain.
Key Characteristics
- Typically begins between ages 50-70
- Affects both sides of the brain
- Progressive deterioration over 6-8 years
- No known cure, but symptoms can be managed
Common Symptoms
Movement-Related
- Stiffness and slowness of movement
- Involuntary muscle jerks or twitches
- Difficulties with balance and walking
- "Alien limb" phenomenon
- Poor coordination
Cognitive and Behavioral
- Speech difficulties
- Memory problems
- Difficulty with complex tasks
- Changes in personality
- Depression or anxiety
Diagnosis
Diagnostic Process
- Detailed medical history
- Neurological examination
- Brain imaging (MRI, CT scan)
- Neuropsychological testing
Treatment Options
Medication Management
- Levodopa for movement symptoms
- Muscle relaxants
- Antidepressants when needed
Supportive Therapies
- Physical therapy
- Occupational therapy
- Speech therapy
- Psychological support
Living with CBD
Daily Management
- Regular exercise as tolerated
- Home safety modifications
- Assistive devices as needed
- Regular medical follow-up
Support Resources
- Support groups
- Family counseling
- Social services
- Caregiver assistance
Research and Outlook
- Ongoing clinical trials
- Research into causes
- Development of new treatments
- Genetic studies