Endoscopic Polypectomy: Clinical Protocol and Best Practices

A Comprehensive Guide for Gastroenterologists

Gastroenterology

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Last updated: Mar 24, 2025

Pre-Procedure Assessment

Patient Evaluation

  • Review complete medical history
  • Assess anticoagulation status
  • Evaluate comorbidities
  • Review imaging and previous endoscopy reports

Equipment Preparation

  • Snares (various sizes)
  • Hot and cold biopsy forceps
  • Injection needles (23-25 gauge)
  • Hemoclips
  • Retrieval devices

Procedure Steps

1. Initial Assessment

  • Document polyp characteristics:
    • Size
    • Morphology (Paris classification)
    • Surface pattern
    • Location

2. Technique Selection

Cold Snare Polypectomy

  • Indicated for polyps ≤10mm
  • No electrocautery required
  • Reduced risk of delayed bleeding

Hot Snare Polypectomy

  • For polyps >10mm
  • Electrocautery settings:
    • ENDO CUT Q: Effect 3
    • Duration 1, Interval 6

3. Execution

  1. Position polyp at 5-6 o'clock
  2. Place snare wire around polyp
  3. Ensure 1-2mm margin of normal mucosa
  4. Close snare slowly and verify tissue capture
  5. Remove specimen

Post-Procedure

Specimen Handling

  • Label specimens separately
  • Document retrieval method
  • Submit to pathology in formalin

Documentation Requirements

  • Polyp characteristics
  • Removal technique
  • Complications
  • Retrieved specimen details

Complications Management

Immediate

  • Bleeding: Implement hemostasis protocol
  • Perforation: Assess for clip closure

Delayed

  • Post-polypectomy syndrome
  • Delayed bleeding
  • Monitor for 14 days

Quality Metrics

  • Complete retrieval rate
  • Clean resection margins
  • Complication rates
  • Follow-up compliance

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