Heart-Lung Transplant: A Comprehensive Guide

Understanding Combined Heart and Lung Transplantation

Cardiac Surgery

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Last updated: Mar 24, 2025

What Is a Heart-Lung Transplant?

A heart-lung transplant is a complex surgical procedure where both the heart and lungs of a patient are replaced with healthy donor organs simultaneously. This procedure is reserved for patients with severe combined heart and lung disease.

When Is It Needed?

  • End-stage heart and lung disease
  • Severe pulmonary hypertension with heart failure
  • Complex congenital heart defects
  • Severe cardiopulmonary conditions unresponsive to other treatments

The Transplant Process

Pre-Transplant Evaluation

  • Comprehensive medical assessment
  • Psychological evaluation
  • Financial and support system review
  • Extensive testing including:
    • Blood work
    • Imaging studies
    • Cardiac catheterization
    • Pulmonary function tests

The Surgery

  1. Anesthesia and preparation
  2. Removal of diseased organs
  3. Implantation of donor heart and lungs
  4. Connection of blood vessels and airways
  5. Closure and immediate post-operative care

Recovery and Aftercare

Hospital Stay (4-6 weeks)

  • Intensive care monitoring
  • Breathing support
  • Pain management
  • Physical therapy initiation

Long-Term Management

  • Medications:
    • Immunosuppressants
    • Anti-infection drugs
    • Heart medications
  • Regular follow-up appointments
  • Lifestyle modifications

Risks and Complications

Early Complications

  • Organ rejection
  • Infection
  • Bleeding
  • Primary graft failure

Long-Term Considerations

  • Chronic rejection
  • Side effects of immunosuppression
  • Increased cancer risk
  • Infections

Living with a Heart-Lung Transplant

  • Regular exercise as advised
  • Balanced nutrition
  • Infection prevention
  • Medication adherence
  • Regular medical monitoring

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