Japanese Encephalitis: A Patient's Guide

Understanding Prevention, Symptoms, and Treatment

Neurology

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Last updated: Mar 24, 2025

What is Japanese Encephalitis?

Japanese encephalitis (JE) is a serious viral infection spread by mosquitoes that affects the brain. It's most common in rural areas of Asia and the Pacific regions.

Key Facts

  • Caused by a flavivirus transmitted through mosquito bites
  • Most common in rural agricultural areas
  • Occurs mainly during rainy seasons
  • Pigs and wading birds serve as virus reservoirs

Symptoms

Initial Symptoms (1-6 days after infection):

  • High fever (38°C/100.4°F or higher)
  • Headache
  • Fatigue
  • Nausea and vomiting

Severe Symptoms:

  • Neck stiffness
  • Seizures
  • Confusion
  • Paralysis
  • Loss of consciousness

Risk Factors

  • Living in or traveling to endemic areas
  • Outdoor activities in rural areas
  • Proximity to pig farms or rice paddies
  • Lack of vaccination

Prevention

  1. Vaccination

    • Recommended for travelers to endemic areas
    • Two-dose series for most adults
  2. Mosquito Protection

    • Use insect repellent
    • Wear long sleeves and pants
    • Stay in screened accommodations
    • Avoid outdoor activities at dawn and dusk

Treatment

  • No specific antiviral treatment exists
  • Supportive care focuses on:
    • Managing fever
    • Controlling seizures
    • Reducing intracranial pressure
    • Providing respiratory support if needed

Recovery and Outlook

  • Recovery time varies significantly
  • 20-30% of cases result in death
  • Among survivors:
    • 30-50% have neurological complications
    • Recovery can take several months

When to Seek Medical Care

Seek immediate medical attention if you develop symptoms after visiting an endemic area, especially:

  • High fever with headache
  • Mental status changes
  • Seizures
  • Neck stiffness

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