Melanoma Detection: The ABCDE Warning Signs

A Guide to Early Recognition of Skin Cancer

Dermatology

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Last updated: Mar 24, 2025

Understanding Melanoma Warning Signs

Melanoma is a serious form of skin cancer that requires early detection for the best outcomes. Learn these essential warning signs using the ABCDE rule:

The ABCDE Rule

A - Asymmetry

  • One half of the mole doesn't match the other half
  • Healthy moles are typically symmetrical

B - Border

  • Irregular, notched, or ragged borders
  • Normal moles have smooth, even borders

C - Color

  • Multiple colors or uneven coloring
  • Watch for variations in brown, tan, black
  • Red, white, or blue areas are concerning

D - Diameter

  • Larger than 6 millimeters (pencil eraser size)
  • Though smaller melanomas are possible

E - Evolution

  • Changes in size, shape, or color over time
  • New symptoms like itching or bleeding

Additional Warning Signs

  • New moles appearing in adulthood
  • Moles that look different from others ("ugly duckling" sign)
  • Sores that don't heal

When to Seek Medical Attention

Contact your dermatologist if you notice:

  • Any of the ABCDE warning signs
  • Changes in existing moles
  • Unusual skin changes

Prevention Tips

  1. Monthly self-skin examinations
  2. Annual professional skin checks
  3. Sun protection (SPF 30+)
  4. Protective clothing
  5. Avoiding peak UV hours

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