Oncology Practice Emergency Response Protocols

Standard Operating Procedures for Critical Oncological Emergencies

Oncology

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Last updated: Mar 24, 2025

1. Immediate Response Procedures

1.1 Chemotherapy Extravasation

  • Immediately stop infusion
  • Document site and medication involved
  • Apply appropriate antidote based on vesicant type:
    • Dexrazoxane for anthracyclines
    • Sodium thiosulfate for mechlorethamine
    • Cold/warm compresses as indicated
  • Photograph the site
  • Complete incident report

1.2 Anaphylactic Reactions

  • Stop drug administration immediately
  • Call emergency response team
  • Administer:
    • Epinephrine 0.3-0.5mg IM
    • Diphenhydramine 50mg IV
    • Hydrocortisone 100mg IV
  • Monitor vital signs q5min

2. Critical Care Equipment Requirements

2.1 Emergency Cart Contents

  • Resuscitation equipment
  • Emergency medications
  • Extravasation kit
  • Spill kit
  • Documentation forms

2.2 Location Requirements

  • Emergency cart in each treatment area
  • Backup supplies in designated storage
  • Clear access paths maintained

3. Staff Responsibilities

3.1 Primary Response Team

  • Oncologist on call
  • Charge nurse
  • Infusion nurse
  • Emergency response coordinator

3.2 Secondary Support

  • Pharmacy staff
  • Administrative personnel
  • Security team

4. Documentation Requirements

4.1 Incident Reports

  • Patient information
  • Event description
  • Actions taken
  • Outcomes
  • Staff involved

4.2 Follow-up Procedures

  • Patient monitoring protocol
  • Incident review
  • Protocol updates as needed
  • Staff debriefing

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