What is AIS?
Androgen Insensitivity Syndrome (AIS) is a genetic condition that affects sexual development. It occurs when the body cannot respond properly to androgens (male hormones) due to a variation in the androgen receptor gene.
Types of AIS
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Complete AIS (CAIS): Complete insensitivity to androgens
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Partial AIS (PAIS): Partial response to androgens
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Mild AIS (MAIS): Mild androgen resistance
Characteristics
Complete AIS
- External female appearance
- Female gender identity
- Absence of uterus and ovaries
- Presence of undescended testes
- Lack of body hair
- Normal breast development
Partial AIS
- Varying degrees of genital development
- Mixed masculine and feminine characteristics
- Variable gender identity
Diagnosis
- Genetic testing
- Physical examination
- Hormone level testing
- Family history evaluation
- Imaging studies
Management
Medical Care
- Hormone replacement therapy
- Regular monitoring
- Psychological support
- Surgical options when appropriate
Long-term Considerations
- Bone health monitoring
- Regular medical check-ups
- Fertility counseling
- Support group participation
Living with AIS
- Understanding your condition
- Building a support network
- Regular medical care
- Genetic counseling for family planning
Support Resources
- AIS support groups
- Mental health professionals
- Genetic counselors
- Endocrinology specialists