Understanding Antidepressant Medications

A Comprehensive Guide for Patients

Psychiatry

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Last updated: Mar 24, 2025

What Are Antidepressants?

Antidepressants are prescription medications that help treat depression, anxiety, and other mental health conditions. They work by balancing certain brain chemicals called neurotransmitters.

Types of Antidepressants

SSRIs (Selective Serotonin Reuptake Inhibitors)

  • Common examples: fluoxetine (Prozac), sertraline (Zoloft), escitalopram (Lexapro)
  • How they work: Increase serotonin levels in the brain
  • Usually prescribed first due to fewer side effects

SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors)

  • Common examples: venlafaxine (Effexor), duloxetine (Cymbalta)
  • How they work: Increase both serotonin and norepinephrine

Other Types

  • Tricyclic antidepressants (TCAs)
  • MAO inhibitors (MAOIs)
  • Atypical antidepressants

Important Information

Starting Treatment

  • Takes 2-6 weeks to feel full effects
  • Start with low doses
  • Regular monitoring by healthcare provider

Side Effects

  • Nausea
  • Sleep changes
  • Dry mouth
  • Weight changes
  • Sexual side effects

Safety Considerations

  1. Never stop suddenly - always taper under medical supervision
  2. Inform your doctor about other medications
  3. Avoid alcohol while taking antidepressants
  4. Report any unusual symptoms promptly

When to Contact Your Doctor

  • Severe side effects
  • Worsening depression
  • Suicidal thoughts
  • Need to stop medication

Treatment Success

  • Take medication regularly
  • Keep all follow-up appointments
  • Combine with therapy when recommended
  • Maintain healthy lifestyle habits

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