What is ADPKD?
Autosomal Dominant Polycystic Kidney Disease is a genetic disorder characterized by the growth of numerous cysts in the kidneys. These fluid-filled sacs can significantly enlarge the kidneys and impair their function over time.
Key Features
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Inherited condition: Passed from parent to child with a 50% chance of inheritance
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Progressive disease: Symptoms typically develop between ages 30-40
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Bilateral involvement: Affects both kidneys
Common Symptoms
- High blood pressure
- Back or side pain
- Blood in urine
- Kidney stones
- Urinary tract infections
- Enlarged abdomen
Diagnosis
Primary Diagnostic Tools
- Imaging tests
- Genetic testing
- Family history evaluation
Treatment Options
Conservative Management
- Blood pressure control
- Healthy lifestyle modifications
- Pain management
- Regular monitoring
Medications
- Tolvaptan (to slow cyst growth)
- Antihypertensive medications
- Pain relievers as needed
Advanced Treatment
- Dialysis (when necessary)
- Kidney transplantation
Living with ADPKD
Lifestyle Recommendations
- Maintain healthy blood pressure
- Stay well-hydrated
- Limit salt intake
- Exercise regularly
- Avoid smoking
Complications
- Chronic kidney disease
- Heart valve abnormalities
- Liver cysts
- Brain aneurysms
- Chronic pain
Monitoring and Follow-up
- Regular blood pressure checks
- Kidney function tests
- Periodic imaging
- Annual medical review
Support and Resources
- PKD Foundation
- Genetic counseling
- Support groups
- Mental health services