Understanding Coeliac Disease

A Comprehensive Guide to Gluten Sensitivity

Gastroenterology

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Last updated: Mar 24, 2025

What is Coeliac Disease?

Coeliac disease is an autoimmune condition where the body's immune system reacts abnormally to gluten, causing damage to the small intestine's lining.

Key Facts

  • Affects approximately 1% of the population
  • Genetic predisposition plays a significant role
  • Cannot be outgrown - it's a lifelong condition
  • Must be managed through strict dietary changes

Common Symptoms

Digestive Symptoms

  • Diarrhea
  • Bloating and gas
  • Abdominal pain
  • Nausea
  • Weight loss

Non-digestive Symptoms

  • Fatigue
  • Iron-deficiency anemia
  • Skin rash (dermatitis herpetiformis)
  • Joint pain
  • Depression or anxiety

Diagnosis

  1. Blood tests to check for specific antibodies
  2. Genetic testing
  3. Intestinal biopsy (gold standard)

Treatment

Gluten-Free Diet

The only effective treatment is a strict gluten-free diet, avoiding:

  • Wheat
  • Barley
  • Rye
  • Some oat products

Monitoring

  • Regular follow-up with healthcare providers
  • Blood tests to monitor antibody levels
  • Nutritional assessment

Complications if Untreated

  • Malnutrition
  • Osteoporosis
  • Infertility
  • Increased risk of certain cancers

Living with Coeliac Disease

Tips for Success

  • Read food labels carefully
  • Learn about hidden sources of gluten
  • Join support groups
  • Plan ahead when eating out

When to Seek Medical Help

  • Persistent digestive symptoms
  • Unexplained weight loss
  • Family history of coeliac disease
  • Ongoing fatigue or weakness

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