Understanding Diphtheria

A Comprehensive Guide to Prevention, Symptoms, and Treatment

Pediatrics

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Last updated: Mar 24, 2025

What is Diphtheria?

Diphtheria is a serious bacterial infection caused by Corynebacterium diphtheriae. It primarily affects the mucous membranes of the nose and throat.

Key Symptoms

  • Thick, gray coating in the throat and nose
  • Difficulty breathing or swallowing
  • Swollen neck glands ('bull neck')
  • Fever and chills
  • General weakness

Transmission

Diphtheria spreads through:

  • Respiratory droplets from coughing or sneezing
  • Close physical contact with an infected person
  • Touching contaminated objects

Risk Factors

  • Unvaccinated status
  • Travel to endemic areas
  • Weakened immune system
  • Poor living conditions

Complications

Untreated diphtheria can lead to:

  • Heart problems
  • Nerve damage
  • Breathing difficulties
  • Paralysis
  • Death in severe cases

Diagnosis

  • Physical examination
  • Throat culture
  • Laboratory tests

Treatment

  1. Antitoxin Therapy
    • Immediate administration of diphtheria antitoxin
  2. Antibiotics
    • Usually penicillin or erythromycin
  3. Supportive Care
    • Rest
    • Proper nutrition
    • Respiratory support if needed

Prevention

  1. Vaccination
    • DTaP for children
    • Td/Tdap boosters for adults
  2. Isolation of infected individuals
  3. Good hygiene practices

When to Seek Medical Care

Seek immediate medical attention if you:

  • Have been exposed to diphtheria
  • Develop symptoms
  • Haven't been vaccinated and plan to travel to high-risk areas

Prognosis

With prompt treatment, most people recover fully. Delayed treatment increases risk of complications.

Follow-up Care

  • Complete full course of antibiotics
  • Regular medical check-ups
  • Ensure vaccination status is current

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