Understanding Gangrene: A Patient's Guide

Essential Information About Causes, Symptoms, and Treatment Options

Vascular Surgery

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Last updated: Mar 24, 2025

What is Gangrene?

Gangrene is the death of body tissue due to either a lack of blood flow or a serious bacterial infection. It commonly affects the extremities, including fingers, toes, and limbs, but can also occur in internal organs.

Types of Gangrene

  • Dry gangrene: Caused by poor blood supply
  • Wet gangrene: Involves bacterial infection
  • Gas gangrene: A severe form caused by specific bacteria
  • Internal gangrene: Affects internal organs
  • Fournier's gangrene: A rare type affecting the genitals

Risk Factors

  • Diabetes
  • Peripheral arterial disease
  • Smoking
  • Severe injury or trauma
  • Weakened immune system
  • Obesity

Common Symptoms

External Gangrene

  • Skin discoloration (black, blue, or brown)
  • Cold and numb sensation
  • Pain in affected area
  • Foul-smelling discharge (in wet gangrene)
  • Swelling and blistering

Internal Gangrene

  • Severe pain
  • Fever
  • Confusion
  • Low blood pressure
  • Vomiting

Diagnosis

  • Physical examination
  • Blood tests
  • Imaging tests (X-rays, CT scans, MRI)
  • Tissue cultures

Treatment Options

  1. Immediate Medical Care

    • Antibiotics for infection
    • Pain management
    • Wound care
  2. Surgical Interventions

    • Debridement (removal of dead tissue)
    • Amputation (if necessary)
    • Revascularization procedures
  3. Supportive Treatments

    • Hyperbaric oxygen therapy
    • Wound dressings
    • Rehabilitation

Prevention

  • Control diabetes and blood pressure
  • Stop smoking
  • Practice good hygiene
  • Protect from injury
  • Regular medical check-ups

When to Seek Medical Help

Seek immediate medical attention if you notice:

  • Persistent skin discoloration
  • Unexplained pain
  • Signs of infection
  • Loss of sensation

Recovery and Outlook

Recovery depends on:

  • Type and extent of gangrene
  • Promptness of treatment
  • Overall health condition
  • Compliance with treatment plan

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