Understanding GERD Medications: A Patient's Guide to Treatment Options

A comprehensive overview of medications used to manage gastroesophageal reflux disease

Gastroenterology

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Last updated: Mar 24, 2025

Overview

Gastroesophageal reflux disease (GERD) often requires medication to manage symptoms effectively. This guide explains the main types of medications used.

Categories of GERD Medications

1. Antacids

  • Purpose: Provide quick, temporary relief
  • Examples: Calcium carbonate, magnesium hydroxide
  • Usage: Take as needed for immediate symptom relief

2. H2 Blockers

  • Purpose: Reduce acid production
  • Examples: Famotidine, ranitidine
  • Duration: Work for 12-24 hours

3. Proton Pump Inhibitors (PPIs)

  • Purpose: Block acid production
  • Examples: Omeprazole, esomeprazole
  • Usage: Take daily before first meal

Important Considerations

Timing of Medications

  • Take PPIs 30-60 minutes before eating
  • Space antacids 2 hours from other medications
  • Follow prescribed dosing schedule

Side Effects to Monitor

  • Headaches
  • Nausea
  • Vitamin B12 deficiency (long-term PPI use)
  • Magnesium deficiency

When to Contact Your Doctor

  • Persistent symptoms despite medication
  • New or worsening side effects
  • Questions about long-term use

Lifestyle Modifications

Medications work best when combined with:

  • Dietary changes
  • Weight management
  • Elevated head of bed
  • Avoiding late meals

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