What is Hodgkin Lymphoma?
Hodgkin lymphoma (HL) is a type of cancer that starts in the lymphatic system, specifically affecting white blood cells called lymphocytes. It's distinguished from other lymphomas by the presence of Reed-Sternberg cells, which are abnormal large cells visible under a microscope.
Types of Hodgkin Lymphoma
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Classical Hodgkin Lymphoma (cHL)
- Nodular sclerosis
- Mixed cellularity
- Lymphocyte-rich
- Lymphocyte-depleted
-
Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL)
Common Symptoms
- Painless swelling of lymph nodes (neck, armpit, groin)
- Persistent fatigue
- Fever and night sweats
- Unexplained weight loss
- Itching
- Cough or breathing difficulties
Diagnosis
Initial Assessment
- Physical examination
- Medical history review
- Blood tests
Confirmatory Tests
- Lymph node biopsy
- Imaging studies (PET-CT scan)
- Bone marrow biopsy (if needed)
Treatment Options
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Chemotherapy
- ABVD regimen is most common
- Treatment cycles typically last 2-8 months
-
Radiation Therapy
- Often combined with chemotherapy
- Targeted to affected areas
-
Immunotherapy
- For relapsed or resistant cases
- Includes targeted antibody treatments
Prognosis and Recovery
- High cure rates (>80% for early stages)
- Regular follow-up care essential
- Long-term monitoring for late effects
Living with Hodgkin Lymphoma
- Maintain healthy lifestyle
- Follow medical advice closely
- Seek emotional support
- Join support groups
When to Contact Your Healthcare Team
- New or worsening symptoms
- Treatment side effects
- Unexplained fever
- Severe pain or discomfort