Understanding Molar Pregnancy

A Comprehensive Guide to Hydatidiform Mole

Family Medicine

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Last updated: Mar 24, 2025

What is a Molar Pregnancy?

A molar pregnancy (hydatidiform mole) is an abnormal form of pregnancy where placental tissue develops into an abnormal mass of cysts instead of a normal fetus. This occurs due to problems during fertilization.

Types of Molar Pregnancy

  • Complete Molar Pregnancy

    • No fetal tissue develops
    • Only abnormal placental tissue is present
    • Contains no maternal chromosomes
  • Partial Molar Pregnancy

    • Some fetal tissue may develop
    • Contains both maternal and paternal chromosomes
    • Not viable for normal development

Common Symptoms

  • Vaginal bleeding (often dark brown to bright red)
  • Severe nausea and vomiting
  • Grape-like cysts passing from vagina
  • Unusually high hCG levels
  • Rapid uterine growth
  • High blood pressure (in some cases)

Risk Factors

  • Age over 35 or under 20
  • Previous molar pregnancy
  • History of miscarriage
  • Asian ethnicity
  • Dietary deficiencies

Diagnosis

  1. Blood tests (hCG levels)
  2. Ultrasound examination
  3. Physical examination
  4. Medical history review

Treatment Options

  • Dilation and Curettage (D&C)

    • Primary treatment method
    • Removes abnormal tissue
  • Follow-up Care

    • Regular hCG monitoring
    • Contraception recommended
    • Duration: 6-12 months

Potential Complications

  • Persistent trophoblastic disease
  • Choriocarcinoma (rare)
  • Emotional trauma
  • Future pregnancy concerns

Recovery and Future Pregnancy

  • Wait 6-12 months before trying to conceive
  • Success rate for future pregnancies is high
  • Increased monitoring in subsequent pregnancies
  • Regular check-ups recommended

When to Seek Medical Care

  • Abnormal vaginal bleeding
  • Severe nausea/vomiting
  • Pelvic pain or pressure
  • Grape-like tissue passage
  • Any pregnancy symptoms that seem unusual

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