Understanding Multiple Myeloma

A Comprehensive Guide to Blood Cancer of Plasma Cells

Oncology

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Last updated: Mar 24, 2025

What is Multiple Myeloma?

Multiple myeloma is a type of blood cancer that develops in plasma cells, which are specialized white blood cells that produce antibodies to fight infections. When these cells become cancerous, they multiply uncontrollably and produce abnormal proteins that can damage various organs.

Key Symptoms

  • Bone pain, especially in the spine and chest
  • Frequent infections
  • Fatigue and weakness
  • Unexplained weight loss
  • Easily broken bones
  • Numbness or weakness in legs
  • Excessive thirst and frequent urination

Risk Factors

  • Age (most common in people over 60)
  • Male gender
  • African American ethnicity
  • Family history
  • Obesity
  • Previous radiation exposure

Diagnosis

Diagnosis typically involves:

  1. Blood tests (including protein electrophoresis)
  2. Urine tests
  3. Bone marrow biopsy
  4. Imaging studies (X-rays, MRI, CT, or PET scans)

Treatment Options

Primary Treatments

  • Chemotherapy
  • Targeted therapy
  • Immunotherapy
  • Stem cell transplantation

Supportive Treatments

  • Radiation therapy
  • Pain management
  • Bone-strengthening medications
  • Regular monitoring

Living with Multiple Myeloma

Self-Care Strategies

  • Regular exercise as tolerated
  • Balanced nutrition
  • Infection prevention
  • Regular medical follow-up
  • Stress management

Prognosis

While multiple myeloma remains incurable, modern treatments have significantly improved survival rates and quality of life. Many patients live for years or decades with proper management.

When to Seek Medical Attention

Contact your healthcare provider if you experience:

  • Persistent bone pain
  • Unusual bruising or bleeding
  • Frequent infections
  • Severe fatigue
  • Sudden weight loss

Support Resources

  • Support groups
  • Patient advocacy organizations
  • Mental health services
  • Financial assistance programs

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