Understanding Overactive Thyroid (Hyperthyroidism)

A Comprehensive Guide to Causes, Symptoms, and Treatment Options

Endocrinology

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Last updated: Mar 24, 2025

What is Hyperthyroidism?

Hyperthyroidism occurs when your thyroid gland produces excessive amounts of thyroid hormones (T3 and T4). These hormones control many important bodily functions, including metabolism, heart rate, and body temperature.

Common Causes

  • Graves' Disease: An autoimmune disorder (most common cause)
  • Toxic Nodular Goiter: Overactive thyroid nodules
  • Thyroiditis: Inflammation of the thyroid gland
  • Excessive iodine intake
  • Medication-induced: Some medications can affect thyroid function

Key Symptoms

Physical Symptoms:

  • Rapid heartbeat (tachycardia)
  • Unexplained weight loss
  • Excessive sweating
  • Tremors in hands and fingers
  • Muscle weakness

Mental/Emotional Symptoms:

  • Anxiety and nervousness
  • Irritability
  • Sleep difficulties
  • Difficulty concentrating

Diagnosis

  1. Blood Tests:
    • TSH (Thyroid Stimulating Hormone)
    • Free T4 and T3 levels
  2. Radioactive Iodine Uptake Test
  3. Thyroid Scan
  4. Physical Examination

Treatment Options

Medications:

  • Anti-thyroid drugs (methimazole, propylthiouracil)
  • Beta-blockers for symptom relief

Other Treatments:

  • Radioactive iodine therapy
  • Thyroid surgery (thyroidectomy)
  • Lifestyle modifications

Complications if Untreated

  • Heart problems
  • Osteoporosis
  • Eye problems (especially with Graves' disease)
  • Thyroid storm (rare but serious)

Living with Hyperthyroidism

  • Regular medical check-ups
  • Medication compliance
  • Balanced diet
  • Stress management
  • Regular exercise as tolerated

When to Seek Medical Care

  • Rapid heart rate
  • Severe anxiety
  • Unusual weakness
  • Vision changes
  • Significant weight loss

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