Understanding Vasculitis

A Comprehensive Guide to Blood Vessel Inflammation

Vascular Surgery

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Last updated: Mar 24, 2025

What is Vasculitis?

Vasculitis is a group of conditions characterized by inflammation of blood vessels. This inflammation can cause the vessel walls to thicken, narrow, weaken, or develop scarring, affecting blood flow to various organs and tissues.

Types of Vasculitis

  • Large vessel vasculitis
    • Giant cell arteritis
    • Takayasu's arteritis
  • Medium vessel vasculitis
    • Polyarteritis nodosa
    • Kawasaki disease
  • Small vessel vasculitis
    • ANCA-associated vasculitis
    • IgA vasculitis (Henoch-Schönlein purpura)

Common Symptoms

  • Fever and fatigue
  • Joint and muscle pain
  • Weight loss
  • Skin rashes
  • Nerve problems
  • Organ-specific symptoms depending on affected vessels

Diagnosis

  1. Blood tests
    • Inflammatory markers
    • ANCA testing
    • Complete blood count
  2. Imaging studies
    • Angiography
    • MRI/CT scans
  3. Tissue biopsy

Treatment Options

Primary Treatments

  • Corticosteroids (such as prednisone)
  • Immunosuppressive medications
  • Biological agents

Supportive Care

  • Regular monitoring
  • Lifestyle modifications
  • Prevention of complications

Living with Vasculitis

  • Follow medication schedules strictly
  • Attend regular check-ups
  • Monitor symptoms
  • Maintain a healthy lifestyle
  • Join support groups

When to Seek Medical Care

  • New or worsening symptoms
  • Severe headache or visual changes
  • Chest pain or breathing difficulties
  • Severe abdominal pain
  • Numbness or weakness

Prevention and Management

  1. Take medications as prescribed
  2. Keep all medical appointments
  3. Maintain a healthy diet
  4. Exercise regularly as advised
  5. Avoid smoking
  6. Manage stress effectively

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